The invention relates to a solution comprising: a heteropolyacid and a lanthanide salt in a solvent consisting of a water/organic solvent mixture or an organic solvent. Optionally, the solution can also comprise an organic or inorganic buffer with a pH comprised in the interval of 4-6 or a strong base or acid. The object of the present invention also includes a use of said solution and any products of the reaction between the components thereof as a contrast medium for biological samples and a method for preparing biological samples that uses said solution in at least one step, for analysis by either correlative microscopy (CLEM) and electron microscopy (EM).
CONTRAST SOLUTION FOR THE CHARACTERISATION OF BIOLOGICAL SAMPLES BY ELECTRON OR CORRELATIVE MICROSCOPY
Santi Melissa;Moscardini Aldo;Signore Giovanni;
2020
Abstract
The invention relates to a solution comprising: a heteropolyacid and a lanthanide salt in a solvent consisting of a water/organic solvent mixture or an organic solvent. Optionally, the solution can also comprise an organic or inorganic buffer with a pH comprised in the interval of 4-6 or a strong base or acid. The object of the present invention also includes a use of said solution and any products of the reaction between the components thereof as a contrast medium for biological samples and a method for preparing biological samples that uses said solution in at least one step, for analysis by either correlative microscopy (CLEM) and electron microscopy (EM).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
