Adducins are a family of membrane skeleton proteins encoded by three related genes (ADD1, ADD2 and ADD3 or a-, b- and g-adducin genes). Both ADD1 and ADD3 are ubiquitously expressed, while the b-adducin gene shows a pattern of expression restricted to brain and haematopoietic tissues. Adducin is found as either a heterodimer or heterotetramer of a/b or a/g subunit composition in most tissues. Human erythrocytes mainly contain a/b heterodimers, whereas the g-subunit is also found at low levels in mouse red blood cells (RBCs). [...]
Analysis of the β-adducin gene: new insights into gene structure and function / Costessi, Luisa; relatore esterno: Muro, Andre's Fernando; Scuola Normale Superiore, 2008.
Analysis of the β-adducin gene: new insights into gene structure and function
Costessi, Luisa
2008
Abstract
Adducins are a family of membrane skeleton proteins encoded by three related genes (ADD1, ADD2 and ADD3 or a-, b- and g-adducin genes). Both ADD1 and ADD3 are ubiquitously expressed, while the b-adducin gene shows a pattern of expression restricted to brain and haematopoietic tissues. Adducin is found as either a heterodimer or heterotetramer of a/b or a/g subunit composition in most tissues. Human erythrocytes mainly contain a/b heterodimers, whereas the g-subunit is also found at low levels in mouse red blood cells (RBCs). [...]File | Dimensione | Formato | |
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Costessi_Luisa.pdf
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Descrizione: Doctoral thesis
Tipologia:
Tesi PhD
Licenza:
Solo Lettura
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30.38 MB
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Adobe PDF
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30.38 MB | Adobe PDF |
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