This thesis reports on an in-silico investigation of a few proteins whose function takes part in cell regulation. In particular, this work focuses on selected proteins that carry out their tasks by modifying either the concentration or the nature of inorganic ions within the cell. Among them, there are systems so versatile to even allow, upon proper biotechnological modifications, the creation of new macromolecular entities exploitable in contexts not strictly biological. According to the growing interest towards these two classes of systems alike, both natural proteins and engineered protein-based nanodevices have been considered within this work.

Understanding the working mechanism of natural and engineered proteins for cell regulation and biotechnological applications: a molecular dynamics study / Di Maio, Danilo; relatore: Barone, Vincenzo; Scuola Normale Superiore, 29-Jul-2016.

Understanding the working mechanism of natural and engineered proteins for cell regulation and biotechnological applications: a molecular dynamics study

Di Maio, Danilo
2016

Abstract

This thesis reports on an in-silico investigation of a few proteins whose function takes part in cell regulation. In particular, this work focuses on selected proteins that carry out their tasks by modifying either the concentration or the nature of inorganic ions within the cell. Among them, there are systems so versatile to even allow, upon proper biotechnological modifications, the creation of new macromolecular entities exploitable in contexts not strictly biological. According to the growing interest towards these two classes of systems alike, both natural proteins and engineered protein-based nanodevices have been considered within this work.
29-lug-2016
CHIM/06 CHIMICA ORGANICA
Chimica
cell regulation
Chemistry
molecular dynamics
proteins
Scuola Normale Superiore
Barone, Vincenzo
Brancato, Giuseppe
File in questo prodotto:
File Dimensione Formato  
PhD-Thesis-Di-Maio.pdf

accesso aperto

Descrizione: doctoral thesis full text
Tipologia: Tesi PhD
Licenza: Solo Lettura
Dimensione 73.3 MB
Formato Adobe PDF
73.3 MB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11384/86199
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
  • OpenAlex ND
social impact