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EnglishHere we clone the Xenopus 5-HT2B receptor cDNA and describe its spatio-temporal mRNA expression within the developing larval brain and visual system. Expression of the 5-HT2B transcripts is compared to that of 5-HT2C as well as proliferation and neurogenic markers. In developing brain and retina, 5-HT2B and 2C mRNAs are mainly expressed in proliferative regions. We suggest that these receptors may play a role in the larval secondary neurogenesis by mediating mitogenic effects of serotonin.
| Titolo: | Expression of 5-HT2B and 5-HT2C receptor genes is associated with proliferative regions of Xenopus developing brain and eye |
| Autori: | |
| Data di pubblicazione: | 2003 |
| Rivista: | |
| Parole Chiave: | 5-HT2B receptor, Serotonin receptors, Nervous system development, Secondary neurogenesis, Retina, Xenopus |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/S0169-328X(03)00173-6 |
| Handle: | http://hdl.handle.net/11384/7401 |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
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