Protein corona alleviates adverse biological effects of nanoplastics in breast cancer cells

Pollution from micro- and nanoplastics (MNPs) has long been a topic of concern due to its potential impact on human health. MNPs can circulate through human blood and, thus far, have been found in the lungs, spleen, stomach, liver, kidneys and even in the brain, placenta, and breast milk. While data are already available on the adverse biological effects of pristine MNPs (e.g. oxidative stress, inflammation, cytotoxicity, and even cancer induction), no report thus far clarified whether the sa...

Enhancing Immune Responses against SARS-CoV-2 Variants in Aged Mice with INDUK: A Chimeric DNA Vaccine Encoding the Spike S1-TM Subunits

Currently available vaccines against COVID-19 showed high efficacy against the original strain of SARS-CoV-2 but progressively lower efficacy against new variants. In response to emerging SARS-CoV-2 strains, we propose chimeric DNA vaccines encoding the spike antigen, including a combination of selected key mutations from different variants of concern. We developed two DNA vaccines, pVAX-S1-TM-D614G and pVAX-S1-TM-INDUK (INDUK), encoding the SARS-CoV-2 S1 spike subunit in fusion with the tran...

[Recensione a ] M. Schmelzer, A. Vetter, A. Vansintjan, The future is degrowth : a guide to a world beyond capitalism, London & New York, Verso, 2022

Accurate simultaneous constraints on the dust mass, temperature, and emissivity index of a galaxy at redshift 7.31

We present new multifrequency Atacama Large Millimeter/submillimeter Array (ALMA) continuum observations of the massive [ log 10 ( M∗ / M ⊙) = 10 . 3 + 0 . 1 -0. 2 ], UV-luminous [ M UV = -21 . 7 ±0 . 2] z = 7 . 31 galaxy REBELS-25 in Bands 3, 4, 5, and 9. Combining the new observations with previously taken data in Bands 6 and 8, we co v er the dust continuum emission of the galaxy in six distinct bands -spanning rest-frame 50 -350 μm -enabling simultaneous constraints on its dust mass ( M d...