MALERBA, FRANCESCA
MALERBA, FRANCESCA
Classe di Scienze
A new mechanism for Alzheimer neurodegeneration: functional antagonism between proNGF, mature NGF and their receptors
2009-01-01 Capsoni, Simona; Fasulo, L; Tiveron, C; Scardigli, R; Paoletti, Francesca; Malerba, Francesca; LA REGINA, F; Brandi, R; Vignone, D; Pistillo, L; Amato, G; Lecci, A; Meli, GIOVANNI ANTONIO; Cattaneo, Antonino
A quantitative bioassay to determine the inhibitory potency of NGF-TrkA antagonists
2021-01-01 Malerba, Francesca; Bruni Ercole, Bruno; Florio, Rita; Cattaneo, Antonino
Conformational Rigidity within Plasticity Promotes Differential Target Recognition of Nerve Growth Factor
2016-01-01 Paoletti, Francesca; de Chiara, Cesira; Kelly, Geoff; Covaceuszach, Sonia; Malerba, Francesca; Yan, Robert; Lamba, Doriano; Cattaneo, Antonino; Pastore, Annalisa
Congenital pain insensitivity mutation in nerve growth factor gene uncouples nociception from central features of pain in heterozygous humans and mice
2018-01-01 Testa, G; Perini, I; Mainardi, M; Morelli, C; Olimpico, F; Pancrazi, L; Petrella, C; Severini, C; Florio, R; Malerba, F; Heppenstall, P; Costa, M; Morrison, I; Capsoni, S; Cattaneo, A
Functional Characterization of Human ProNGF and NGF Mutants: Identification of NGF P61SR100E as a "Painless" Lead Investigational Candidate for Therapeutic Applications
2015-01-01 Malerba, Francesca; Paoletti, Francesca; Bruni Ercole, Bruno; Materazzi, Serena; Nassini, Romina; Coppi, Elisabetta; Patacchini, Riccardo; Capsoni, Simona; Lamba, Doriano; Cattaneo, Antonino
Identification of proNGF versus NGF expression fingerprinting in PC12 cells
2008-01-01 Arisi, I; Bacalini, Mg; Brandi, R; Capsoni, Simona; D'Onofrio, M; DI MAMBRO, A; Fasulo, L; LA REGINA, F; Lecci, A; Malerba, Francesca; Paoletti, Francesca; Scardigli, R; Tiveron, C; Ugolini, G; Cattaneo, Antonino
Intranasal administration of a painless human NGF reduces memory deficit and amyloid oligomers accumulation in APPxPS1 mice
2011-01-01 Capsoni, Simona; Marinelli, S; Ceci, M; Vignone, D; Amato, G; Malerba, Francesca; Paoletti, Francesca; Pavone, F; Cattaneo, Antonino
Intranasal administration of an optimized human Nerve Growth Factor reduces memory deficits and amyloid oligomers accumulation in APPxPS1 mice
2011-01-01 Capsoni, Simona; Covaceuszach, S; Marinelli, S; Ceci, M; Vignone, D; Amato, G; Paoletti, Francesca; Malerba, Francesca; Ugolini, G; Pavone, F; Cattaneo, Antonino
Involvement of NGF in early stages of chick embryo development
2008-01-01 Capsoni, Simona; Manca, A; DI LUZIO, A; Vignone, D; Malerba, Francesca; Paoletti, Francesca; Cattaneo, Antonino; LEVI MONTALCINI, R.
Nerve growth factor derivative NGF61/100 promotes outgrowth of primary sensory neurons with reduced signs of nociceptive sensitization
2017-01-01 Severini, C; Petrocchi Passeri, P; Ciotti, M. T; Florenzano, F; Petrella, C; Malerba, Francesca; Bruni, B; D'Onofrio, M; Arisi, Ivan; Brandi, R; Possenti, R; Calissano, P; Cattaneo, Antonino
Nerve growth factor neutralization promotes oligodendrogenesis by increasing miR-219a-5p levels
2021-01-01 Brandi, Rossella; Fabiano, Marietta; Giorgi, Corinna; Arisi, Ivan; La Regina, Federico; Malerba, Francesca; Turturro, Sabrina; Storti, Andrea Ennio; Ricevuti, Flavia; Amadio, Susanna; Volontè, Cinzia; Capsoni, Simona; Scardigli, Raffaella; D'Onofrio, Mara; Cattaneo, Antonino
NGF and proNGF Reciprocal Interference in Immunoassays: Open Questions, Criticalities, and Ways Forward
2016-01-01 Malerba, Francesca; Paoletti, Francesca; Cattaneo, Antonino
Over-expression of furin-resistant pro-NGF determines neurodegeneration in transgenic mice
2010-01-01 Capsoni, Simona; Fasulo, L; Tiveron, C; Scardigli, R; Paoletti, Francesca; Malerba, Francesca; LA REGINA, F; Brandi, R; Vignone, D; Pistillo, L; Amato, G; Lecci, A; Meli, GIOVANNI ANTONIO; Cattaneo, Antonino
ProNGF Is a Cell-Type-Specific Mitogen for Adult Hippocampal and for Induced Neural Stem Cells
2019-01-01 Corvaglia, V.; Cilli, D.; Scopa, C.; Brandi, R.; Arisi, I.; Malerba, F.; La Regina, F.; Scardigli, R.; Cattaneo, A.
ProNGF/NGF inbalance triggers neurodegeneration in transgenic mice.
2011-01-01 Fasulo, L; Capsoni, Simona; Tiveron, C; Malerba, Francesca; Paoletti, Francesca; Marinelli, S; Berretta, N; Nistico', R; Brandi, R; Capelli, Paolo; Dalfini, A; D'Aguanno, S; Florenzano, F; Formaggio, E; LA REGINA, F; Pistillo, L; Scardigli, R; Piccinin, S; Vignone, D; Urbani, A; Pavone, F; Cattaneo, Antonino
proNGF/NGF mixtures induce gene expression changes in PC12 cells that neither singly produces
2014-01-01 Arisi, Ivan; D'Onofrio, Mara; Brandi, Rossella; Malerba, Francesca; Paoletti, Francesca; Storti, Andrea Ennio; Florenzano, Fulvio; Fasulo, Luisa; Cattaneo, Antonino
ProNGFNGF imbalance triggers learning and memory deficits, neurodegeneration and spontaneous epileptic-like discharges in transgenic mice
2013-01-01 Tiveron, C; Fasulo, L; Capsoni, Simona; Malerba, Francesca; Marinelli, S; Paoletti, Francesca; Piccinin, S; Scardigli, R; Amato, G; Brandi, R; Capelli, Paolo; D'Aguanno, S; Florenzano, F; La Regina, F; Lecci, A; Manca, A; Meli, GIOVANNI ANTONIO; Pistillo, L; Berretta, N; Nistico, R; Pavone, F; Cattaneo, Antonino
Targeting the cation-chloride co-transporter NKCC1 to re-establish GABAergic inhibition and an appropriate excitatory/inhibitory balance in selective neuronal circuits: a novel approach for the treatment of Alzheimer's disease
2022-01-01 Capsoni, Simona; Arisi, Ivan; Malerba, Francesca; D'Onofrio, Mara; Cattaneo, Antonino; Cherubini, Enrico
The chemokine CXCL12 mediates the anti-amyloidogenic action of painless human nerve growth factor
2017-01-01 Capsoni, Simona; Malerba, Francesca; Carucci, NICOLA MARIA; Rizzi, Caterina; Criscuolo, Chiara; Origlia, Nicola; Calvello, Mariantonietta; Viegi, Alessandro; Meli, Giovanni; Cattaneo, Antonino
The NGFR100W Mutation Specifically Impairs Nociception without Affecting Cognitive Performance in a Mouse Model of Hereditary Sensory and Autonomic Neuropathy Type V
2019-01-01 Testa, G.; Mainardi, M.; Morelli, C.; Olimpico, F.; Pancrazi, L.; Petrella, C.; Severini, C.; Florio, R.; Malerba, F.; Stefanov, A.; Strettoi, E.; Brandi, R.; Arisi, I.; Heppenstall, P.; Costa, M.; Capsoni, S.; Cattaneo, A.